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Fmoc-L-Amino Acids ,  Fmoc-D-Amino Acids,  Fmoc-OPfp Amino Acids,  Boc-L-Amino Acids,  Boc-D-Amino Acids,  Z-Amino Acids,  Unusual Amino Acids,  Amino Acid Derivatives,  N-Methyl Amino Acids,  Amino Acid Alcohols,  Linkers,  Unsubstituted Resins,  Fmoc-Amino Acid-Wang Resins,  Amino Acid 2-Cl-Trt Resins,  MAP Resins,  Pseudoproline Dipeptides,  Reagents  | |||||
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Structure | Catalog# CAS# | Product | Formula MW | Qty/Price* | |
AFR105 [154445-77-9] | Fmoc-Arg(Pbf)-OH Fmoc-Arg(Pbf)-OH has been introduced to reduce the alkylation of tryptophan-containing peptides during final deprotection. Like the Pmc group, the Pbf group of Fmoc-Arg(Pbf)-OH can be cleaved under moderate acid conditions. However, the amount of tryptophan alkylation is significantly reduced, especially in the absence of scavengers. One example reported in the literature showed a 3 hour cleavage and deprotection treatment with TFA resulted 46% of the desired peptide when Fmoc-Arg(Pmc) was used versus 69% when Fmoc-Arg(Pbf) was used (C.G. Fields, G.B. Fields Tetrahedron Lett. 1993, 34, 6661-6664.) | C34H40N4O7S 648.7 | 5g 25g 100g | $ 45 $ 160 $ 455 | |
AFR110 [119831-72-0] | Fmoc-Arg(Pmc)-OH | C35H42N4O7S 662.8 | 5g 25g 100g | $ 50 $ 200 $ 600 | |
AFR120 [83792-47-6] | Fmoc-Arg(Tos)-OH | C28H30N4O6S 550.6 | 25g 100g | $ 155 $ 450 | |
AFR101 [91000-69-0] | Fmoc-Arg-OH | C21H24N4O4 396.4 | 25g 100g | $ 125 $ 375 | |
AFN105 [132388-59-1] | Fmoc-Asn(Trt)-OH Using Fmoc-Asn(Trt)-OH and Fmoc-Gln(Trt)-OH in peptide synthesis prevents the possibility of the amide side chains of Asn and Gln from undergoing dehydration side reactions during activation, especially with carbodiimide reagents. Fmoc-Asn(Trt)-OH and Fmoc-Gln(Trt)-OH also have better solubility properties than Fmoc-Asn-OH or Fmoc-Gln-OH. Fmoc-Asn(Trt)-OH and Fmoc-Gln(Trt)-OH dissolve readily in all standard peptide synthesis reagents, while Fmoc-Asn-OH and Fmoc-Gln-OH are barely soluble in dimethylformamide (DMF). | C38H32N2O5 596.7 | 25g 100g | $ 80 $ 240 | |
AFN101 [71989-16-7] | Fmoc-Asn-OH | C19H18N2O5 354.4 | 100g 500g | $ 60 $ 240 | |
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